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Article

Pharmacogenetics of Drug-Induced QT Interval Prolongation: An Update.

Drug safety - 1 Oct 2015

Niemeijer Maartje N, van den Berg Marten E, Eijgelsheim Mark, Rijnbeek Peter R, Stricker Bruno H

Abstract excerpt

A prolonged QT interval is an important risk factor for ventricular arrhythmias and sudden cardiac death. QT prolongation can be caused by drugs. There are multiple risk factors for drug-induced QT prolongation, including genetic variation. QT prolongation is one of the most common reasons for withdrawal of drugs from the market, despite the fact that these drugs may be beneficial for certain patients and not...

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Identifiers

PMID: 26108299
DOI: 10.1007/s40264-015-0316-6
PMCID: PMC4579250

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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