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Article

Novel multisample scheme for inferring phylogenetic markers from whole genome tumor profiles.

IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000

Subramanian Ayshwarya, Shackney Stanley, Schwartz Russell

Abstract excerpt

Computational cancer phylogenetics seeks to enumerate the temporal sequences of aberrations in tumor evolution, thereby delineating the evolution of possible tumor progression pathways, molecular subtypes, and mechanisms of action. We previously developed a pipeline for constructing phylogenies describing evolution between major recurring cell types computationally inferred from whole-genome tumor profiles. The...

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PMID: 24407301
DOI: 10.1109/TCBB.2013.33
PMCID: PMC3830698

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