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Article

Tracing the tumor lineage.

Molecular oncology - 1 Jun 2010

Navin Nicholas E, Hicks James

Abstract excerpt

Defining the pathways through which tumors progress is critical to our understanding and treatment of cancer. We do not routinely sample patients at multiple time points during the progression of their disease, and thus our research is limited to inferring progression a posteriori from the examination of a single tumor sample. Despite this limitation, inferring progression is possible because the tumor genome...

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Identifiers

PMID: 20537601
DOI: 10.1016/j.molonc.2010.04.010
PMCID: PMC2904844

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