Article
Human autophagy gene<i>ATG16L1</i>is post-transcriptionally regulated by<i>MIR142-3p</i>
6 Jan 2014
Abstract excerpt
Multiple genetic studies have implicated the autophagy-related gene, ATG16L1, in the pathogenesis of Crohn disease (CD). While CD-related research on ATG16L1 has focused on the functional significance of ATG16L1 genetic variations, the mechanisms underlying the regulation of ATG16L1 expression are unclear. Our laboratory has described that microRNAs (miRNAs), key regulators of gene expression, are dysregulated in...
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