Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of ATG16L2 in autophagy and disease

3 Mar 2022

Abstract excerpt

Macroautophagy/autophagy, a fundamental cell process for nutrient recycling and defense against pathogens (termed xenophagy), is crucial to human health. ATG16L2 (autophagy related 16 like 2) is an autophagic protein and a paralog of ATG16L1. Both proteins are implicated in similar diseases such as cancer and other chronic diseases; however, most autophagy studies to date have primarily focused on the function of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine and Purinergic Signaling
Share to Autophagy in Disease and Therapy
Share to Endoplasmic Reticulum Stress and Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35239457
DOI: 10.1080/15548627.2022.2042783

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of ATG16L2 in autophagy and diseasePMID 35239457Read ↗

Distinct Tissue-Specific Roles for the Disease-Associated Autophagy Genes ATG16L2 and ATG16L1Semantic proximity Read ↗

Autophagy and Crohns Disease: At the Crossroads of Infection, Inflammation, Immunity, and CancerSemantic proximity Read ↗

ATG16L1: A multifunctional susceptibility factor in Crohn disease.Semantic proximity Read ↗

The Crohn Disease-associated ATG16L1<sup>T300A</sup> polymorphism regulates inflammatory responses by modulating TLR- and NLR-mediated signalingSemantic proximity Read ↗

Human autophagy gene<i>ATG16L1</i>is post-transcriptionally regulated by<i>MIR142-3p</i>Semantic proximity Read ↗

Functional consequences of mutations in the autophagy genes in the pathogenesis of Crohn's disease.Semantic proximity Read ↗

Myeloid ATG16L1 Facilitates Host-Bacteria Interactions in Maintaining Intestinal Homeostasis.Semantic proximity Read ↗

Autophagy and Crohn's disease.Semantic proximity Read ↗

Alterations of autophagic and innate immune responses by the Crohn's disease-associated ATG16L1 mutation.Semantic proximity Read ↗

ULK1‐mediated phosphorylation of ATG16L1 promotes xenophagy, but destabilizes the ATG16L1 Crohn's mutantSemantic proximity Read ↗

The protein ATG16L1 suppresses inflammatory cytokines induced by the intracellular sensors Nod1 and Nod2 in an autophagy-independent manner.Semantic proximity Read ↗

Role of autophagy and autophagy genes in inflammatory bowel disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.