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Article

Comprehensive genomic profiling of malignant phyllodes tumors of the breast.

Breast cancer research and treatment - 1 Apr 2017

Nozad Sahar, Sheehan Christine E, Gay Laurie M, Elvin Julia A, Vergilio Jo-Anne, Suh James, Ramkissoon Shakti, Schrock Alexa B, Hirshfield Kim M, Ali Nadia, Ganesan Shridar, Ali Siraj M, Miller Vincent A, Stephens Philip J, Ross Jeffrey S, Chung Jon H

Abstract excerpt

PURPOSE: Malignant phyllodes tumors (MPT) are exceptionally rare, and the genomic drivers of these tumors are still being elucidated. We performed comprehensive genomic profiling (CGP) of MPT to identify genomic alterations that will inform approaches to targeted therapy for patients with MPT, including relapsed, refractory, and metastatic disease. METHODS: DNA was extracted from formalin-fixed, paraffin-embedded...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28210881
DOI: 10.1007/s10549-017-4156-1

Genes

BRAF
FGFR3
MED12
TACC3
TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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