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Article

Whole exome sequencing of rare aggressive breast cancer histologies.

Breast cancer research and treatment - 1 Feb 2016

Dieci Maria Vittoria, Smutná Veronika, Scott Véronique, Yin Guangliang, Xu Ran, Vielh Philippe, Mathieu Marie-Christine, Vicier Cécile, Laporte Melanie, Drusch Francoise, Guarneri Valentina, Conte Pierfranco, Delaloge Suzette, Lacroix Ludovic, Fromigué Olivia, André Fabrice, Lefebvre Celine

Abstract excerpt

Little is known about mutational landscape of rare breast cancer (BC) subtypes. The aim of the study was to apply next generation sequencing to three different subtypes of rare BCs in order to identify new genes related to cancer progression. We performed whole exome and targeted sequencing of 29 micropapillary, 23 metaplastic, and 27 pleomorphic lobular BCs. Micropapillary BCs exhibit a profile comparable to...

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PMID: 26907767
DOI: 10.1007/s10549-016-3718-y

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PYGM
CDH1
GATA3

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