Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic hotspots but few recurrent fusion genes in breast cancer.

Genes, chromosomes & cancer - 1 Jul 2018

Fimereli Danai, Fumagalli Debora, Brown David, Gacquer David, Rothé Françoise, Salgado Roberto, Larsimont Denis, Sotiriou Christos, Detours Vincent

Abstract excerpt

The advent of next generation sequencing technologies has boosted the interest in exploring the role of fusion genes in the development and progression of solid tumors. In breast cancer, most of the detected gene fusions seem to be "passenger" events while the presence of recurrent and driver fusions is still under study. We performed RNA sequencing in 55 well-characterized breast cancer samples and 10 adjacent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 17
Share to Chromosomes, Human, Pair 20

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 8

Share to DNA Copy Number Variations

Share to Estrogen Receptor alpha

Share to Gene Fusion

Share to Genes, erbB-2

Share to Genome, Human

Source

Identifiers

PMID: 29436103
DOI: 10.1002/gcc.22533

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic hotspots but few recurrent fusion genes in breast cancer.PMID 29436103Read ↗

Recurrent and pathological gene fusions in breast cancer: current advances in genomic discovery and clinical implications.Semantic proximity Read ↗

Fusion Genes in Breast Cancer.Semantic proximity Read ↗

<scp>Fusion‐associated</scp>carcinomas of the breast: Diagnostic, prognostic, and therapeutic significanceSemantic proximity Read ↗

Gene Fusions Associated with Recurrent Amplicons Represent a Class of Passenger Aberrations in Breast CancerSemantic proximity Read ↗

Comprehensive genome and transcriptome analysis reveals genetic basis for gene fusions in cancerSemantic proximity Read ↗

Characterization of fusion genes in common and rare epithelial ovarian cancer histologic subtypes.Semantic proximity Read ↗

Landscape analysis of adjacent gene rearrangements reveals BCL2L14-ETV6 gene fusions in more aggressive triple-negative breast cancer.Semantic proximity Read ↗

Exploration of the gene fusion landscape of glioblastoma using transcriptome sequencing and copy number dataSemantic proximity Read ↗

Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer.Semantic proximity Read ↗

Dysregulation of cancer genes by recurrent intergenic fusionsSemantic proximity Read ↗

Structural analysis of the genome of breast cancer cell line ZR-75-30 identifies twelve expressed fusion genesSemantic proximity Read ↗

Expressed Gene Fusions as Frequent Drivers of Poor Outcomes in Hormone Receptor–Positive Breast CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.