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Article

Impact of age-associated increase in 2'-O-methylation of miRNAs on aging and neurodegeneration in Drosophila.

Genes & development - 1 Jan 2014

Abe Masashi, Naqvi Ammar, Hendriks Gert-Jan, Feltzin Virzhiniya, Zhu Yongqing, Grigoriev Andrey, Bonini Nancy M

Abstract excerpt

MicroRNAs (miRNAs) are 20- to ∼24-nucleotide (nt) small RNAs that impact a variety of biological processes, from development to age-associated events. To study the role of miRNAs in aging, studies have profiled the levels of miRNAs with time. However, evidence suggests that miRNAs show heterogeneity in length and sequence in different biological contexts. Here, by examining the expression pattern of miRNAs by...

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PMID: 24395246
DOI: 10.1101/gad.226654.113
PMCID: PMC3894412

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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