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Article

The Expression of microRNA and microRNA Clusters in the Aging Heart

18 Apr 2012

Abstract excerpt

BACKGROUND: The microRNAs have been implicated in the process of cardiac development, cardiac hypertrophy, and heart failure. However, the impact of adult aging on cardiac expression of miRNA clusters, as well as both miRNA guide (miR) and passenger (miR*) strands has not been well established. METHODS/RESULTS: We explored the expression profile of both miR and miR* in the hearts of young adult versus old mice....

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PMID: 22529925
DOI: 10.1371/journal.pone.0034688

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