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Article

The Arabidopsis nucleotidyl transferase HESO1 uridylates unmethylated small RNAs to trigger their degradation.

Current biology : CB - 24 Apr 2012

Zhao Yuanyuan, Yu Yu, Zhai Jixian, Ramachandran Vanitharani, Dinh Thanh Theresa, Meyers Blake C, Mo Beixin, Chen Xuemei

Abstract excerpt

MicroRNAs (miRNAs), small interfering RNAs (siRNAs), and piwi-interacting RNAs (piRNAs) impact numerous biological processes in eukaryotes. In addition to biogenesis, turnover contributes to the steady-state levels of small RNAs. One major factor that stabilizes miRNAs and siRNAs in plants as well as siRNAs and piRNAs in animals is 2'-O-methylation on the 3' terminal ribose by the methyltransferase HUA ENHANCER1...

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Identifiers

PMID: 22464194
DOI: 10.1016/j.cub.2012.02.051
PMCID: PMC3350747

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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