Tissue-specific profiling of age-dependent miRNAomic changes in Caenorhabditis elegans

Abstract excerpt

<title>Abstract</title> <p>Ageing in various tissues exhibits common and distinct features. It is critical to decipher the mechanisms underlying ageing in individual tissues. MicroRNAs (miRNAs) are essential regulators in ageing and are recently highlighted as a new class of intercellular signalling molecules. However, little is known about the tissue-specific transcriptomic changes of miRNAs during ageing. <ital...

Topics

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• Aging
• Autophagy in Disease and Therapy
• Biomedical Research
• Caenorhabditis elegans
• Disease Models, Animal
• Drosophila melanogaster
• Gene Knockdown Techniques
• Genetics, Aging, and Longevity in Model Organisms

Identifiers and source

Literature Corpus work

b8dbec10-bbad-5c85-96af-bc3be64b0d94

DOI

10.21203/rs.3.rs-2497512/v1