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Performance and limitations of linkage-disequilibrium-based methods for inferring the genomic landscape of recombination and detecting hotspots: a simulation study

2022-03-31

Abstract excerpt

Knowledge of recombination rate variation along the genome provides important insights into genome and phenotypic evolution. Population genomic approaches offer an attractive way to infer the population-scaled recombination rate ρ=4 N e r using the linkage disequilibrium information contained in DNA sequence polymorphism data. Such methods have been used in a broad range of plant and animal species to build genom...

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Literature Corpus work
f1de66dc-1969-5fd4-a793-b0ee5316ea19
DOI
10.1101/2022.03.30.486352
Open publication

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Performance and limitations of linkage-disequilibrium-based methods for inferring the genomic landscape of recombination and detecting hotspots: a simulation studyDOI 10.1101/2022.03.30.486352
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