Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sequence-level population simulations over large genomic regions.

Genetics - 1 Nov 2007

Hoggart Clive J, Chadeau-Hyam Marc, Clark Taane G, Lampariello Riccardo, Whittaker John C, De Iorio Maria, Balding David J

Abstract excerpt

Simulation is an invaluable tool for investigating the effects of various population genetics modeling assumptions on resulting patterns of genetic diversity, and for assessing the performance of statistical techniques, for example those designed to detect and measure the genomic effects of selection. It is also used to investigate the effectiveness of various design options for genetic association studies....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computer Simulation
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetics, Population

Share to Genomics

Share to Models, Genetic

Share to Recombination, Genetic

Share to Selection, Genetic

Share to Software

Source

Open in PubMed Open full text

Identifiers

PMID: 17947444
DOI: 10.1534/genetics.106.069088
PMCID: PMC2147962

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sequence-level population simulations over large genomic regions.PMID 17947444Read ↗

An overview of population genetic data simulation.Semantic proximity Read ↗

GeneEvolve: a fast and memory efficient forward-time simulator of realistic whole-genome sequence and SNP data.Semantic proximity Read ↗

Population genetic simulations of complex phenotypes with implications for rare variant association tests.Semantic proximity Read ↗

Reproducible simulations of realistic samples for next-generation sequencing studies using Variant Simulation Tools.Semantic proximity Read ↗

ARGON: fast, whole-genome simulation of the discrete time Wright-fisher process.Semantic proximity Read ↗

ARGON: Fast, Whole-Genome Simulation of the Discrete Time Wright-Fisher ProcessSemantic proximity Read ↗

Efficient Coalescent Simulation and Genealogical Analysis for Large Sample Sizes.Semantic proximity Read ↗

Forward-time simulations of human populations with complex diseases.Semantic proximity Read ↗

Genome simulation approaches for synthesizing in silico datasets for human genomics.Semantic proximity Read ↗

GENOME: a rapid coalescent-based whole genome simulator.Semantic proximity Read ↗

Forward-time simulation of realistic samples for genome-wide association studies.Semantic proximity Read ↗

Population size rescaling significantly biases outcomes of forward-in-time population genetic simulations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.