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Article

Chromatin signature of widespread monoallelic expression.

eLife - 31 Dec 2013

Nag Anwesha, Savova Virginia, Fung Ho-Lim, Miron Alexander, Yuan Guo-Cheng, Zhang Kun, Gimelbrant Alexander A

Abstract excerpt

In mammals, numerous autosomal genes are subject to mitotically stable monoallelic expression (MAE), including genes that play critical roles in a variety of human diseases. Due to challenges posed by the clonal nature of MAE, very little is known about its regulation; in particular, no molecular features have been specifically linked to MAE. In this study, we report an approach that distinguishes MAE genes in...

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Identifiers

PMID: 24381246
DOI: 10.7554/eLife.01256
PMCID: PMC3873816

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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