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Article

Synergistic effect of interleukin-10-receptor variants in a case of early-onset ulcerative colitis.

World journal of gastroenterology - 14 Dec 2013

Galatola Martina, Miele Erasmo, Strisciuglio Caterina, Paparo Lorella, Rega Daniela, Delrio Paolo, Duraturo Francesca, Martinelli Massimo, Rossi Giovanni Battista, Staiano Annamaria, Izzo Paola, De Rosa Marina

Abstract excerpt

AIM: To investigated the molecular cause of very early-onset ulcerative colitis (UC) in an 18-mo-old affected child. METHODS: We analysed the interleukin-10 (IL10) receptor genes at the DNA and RNA level in the proband and his relatives. Beta catenin and tumor necrosis factor-α (TNFα) receptors were analysed in the proteins extracted from peripheral blood cells of the proband, his relatives and familial...

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Identifiers

PMID: 24379584
DOI: 10.3748/wjg.v19.i46.8659
PMCID: PMC3870512

Genes

FAP
PTEN

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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