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Article

Interleukin-10 receptor mutations in children with neonatal-onset Crohn's disease and intractable ulcerating enterocolitis.

European journal of gastroenterology & hepatology - 1 Oct 2013

Shim Jung Ok, Hwang Solha, Yang Hye Ran, Moon Jin Soo, Chang Ju Young, Ko Jae Sung, Park Sung Sup, Kang Gyeong-Hoon, Kim Woo Sun, Seo Jeong Kee

Abstract excerpt

Neonatal-onset inflammatory bowel disease (IBD) accounts for only 0.25% of pediatric IBD cases. The molecular pathogenesis of IBD remains unclear. Recently, rare Mendelian mutations have been identified in children with very early-onset Crohn's disease and ulcerative colitis. In this study, we report compound heterozygous mutations in the interleukin-10 receptor A (IL-10RA) gene in children with severe...

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Identifiers

PMID: 23839161
DOI: 10.1097/MEG.0b013e328361a4f9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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