Article
Very early onset inflammatory bowel disease: Investigation of the IL-10 signaling pathway in Iranian children.
European journal of medical genetics - 1 Dec 2017
Nemati Shahram, Teimourian Shahram, Tabrizi Mina, Najafi Mehri, Dara Naghi, Imanzadeh Farid, Ahmadi Mitra, Aghdam Maryam Kazemi, Tavassoli Mohmoud, Rohani Pejman, Madani Seyyed Ramin, de Boer Martin, Kuijpers T W, Roos Dirk
Abstract excerpt
BACKGROUND & AIM: Comparing to adult inflammatory bowel disease (IBD), those with early onset manifestations have different features in terms of the underlying molecular pathology, the course of disease and the response to therapy. We investigated the IL-10 signaling pathway previously reported as an important cause of infantile (Very Early Onset) IBD to find any possible variants. METHOD: With the next...
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