Article
Characterization of SLCO5A1/OATP5A1, a solute carrier transport protein with non-classical function.
PloS one - 1 Jan 2013
Sebastian Katrin, Detro-Dassen Silvia, Rinis Natalie, Fahrenkamp Dirk, Müller-Newen Gerhard, Merk Hans F, Schmalzing Günther, Zwadlo-Klarwasser Gabriele, Baron Jens Malte
Abstract excerpt
Organic anion transporting polypeptides (OATP/SLCO) have been identified to mediate the uptake of a broad range of mainly amphipathic molecules. Human OATP5A1 was found to be expressed in the epithelium of many cancerous and non-cancerous tissues throughout the body but protein characterization and functional analysis have not yet been performed. This study focused on the biochemical characterization of OATP5A1...
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