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Article

Role of Organic Anion-Transporting Polypeptides (OATPs) in Cancer Therapy.

The AAPS journal - 1 May 2015

Thakkar Nilay, Lockhart A Craig, Lee Wooin

Abstract excerpt

The superfamily of organic anion-transporting polypeptides (OATPs, gene symbol SLCO) includes important transporters handling a variety of endogenous and xenobiotic substrates. Currently, 11 human OATPs are known and their substrates include endogenous hormones and their conjugates, anticancer drugs, and imaging agents. The contribution of OATPs to the in vivo disposition of these substrates has been extensively...

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Identifiers

PMID: 25735612
DOI: 10.1208/s12248-015-9740-x
PMCID: PMC4406968

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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