Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Organic anion-transporting polypeptides: a novel approach for cancer therapy

29 Aug 2013

Abstract excerpt

Organic anion-transporting polypeptides (OATPs) encoded by the SLCO genes constitute an important transporter superfamily that mediates transmembrane transport of various clinical drugs and endogenous nutrients. Eleven human OATPs with different transport functions are expressed in various tissues. Bile acids, steroid hormone conjugates, prostaglandins, testosterone and thyroid hormones that promote cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Enzymes and Metabolism
Share to Drug Transport and Resistance Mechanisms
Share to Pharmacological Effects and Toxicity Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23987090
DOI: 10.3109/1061186x.2013.832767

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Organic anion-transporting polypeptides: a novel approach for cancer therapyPMID 23987090Read ↗

Role of Organic Anion-Transporting Polypeptides (OATPs) in Cancer Therapy.Semantic proximity Read ↗

The Expression and Function of Organic Anion Transporting Polypeptides in Normal Tissues and in CancerSemantic proximity Read ↗

Roles of organic anion transporting polypeptides in hepatocellular carcinomaSemantic proximity Read ↗

[Advances in the study of organic anion transporting polypeptide 1B3].Semantic proximity Read ↗

Uptake transporters of the human OATP family: molecular characteristics, substrates, their role in drug-drug interactions, and functional consequences of polymorphisms.Semantic proximity Read ↗

The impact of Organic Anion-Transporting Polypeptides (OATPs) on disposition and toxicity of antitumor drugs: Insights from knockout and humanized miceSemantic proximity Read ↗

Expression of OATP Family Members in Hormone-Related Cancers: Potential Markers of ProgressionSemantic proximity Read ↗

Organic anion transporters: discovery, pharmacology, regulation and roles in pathophysiology.Semantic proximity Read ↗

Genetic polymorphisms of human hepatic OATPs: functional consequences and effect on drug pharmacokineticsSemantic proximity Read ↗

Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family.Semantic proximity Read ↗

The role of OATP1B1 and OATP1B3 transporter polymorphisms in drug disposition and response to anticancer drugs: a review of the recent literatureSemantic proximity Read ↗

Transporters and drug-drug interactions: important determinants of drug disposition and effects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.