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Article

Roles of genetic polymorphisms in the folate pathway in childhood acute lymphoblastic leukemia evaluated by Bayesian relevance and effect size analysis.

PloS one - 1 Jan 2013

Lautner-Csorba Orsolya, Gézsi András, Erdélyi Dániel J, Hullám Gábor, Antal Péter, Semsei Ágnes F, Kutszegi Nóra, Kovács Gábor, Falus András, Szalai Csaba

Abstract excerpt

In this study we investigated whether polymorphisms in the folate pathway influenced the risk of childhood acute lymphoblastic leukemia (ALL) or the survival rate of the patients. For this we selected and genotyped 67 SNPs in 15 genes in the folate pathway in 543 children with ALL and 529 control...

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Identifiers

PMID: 23940529
DOI: 10.1371/journal.pone.0069843
PMCID: PMC3734218

Genes

DHFR
GGH
MTHFD1
MTRR
SHMT1
TYMS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23940529-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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