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Article

SHMT1 C1420T polymorphism contributes to the risk of non-Hodgkin lymphoma: evidence from 7309 patients.

Chinese journal of cancer - 14 Dec 2015

Wang Yi-Wei, Zhang Shao-Dan, Xue Wen-Ji, Zhu Mei-Ling, Zheng Lei-Zhen

Abstract excerpt

BACKGROUND: Serine hydroxymethyltransferase 1 (SHMT1) is a key enzyme in the folate metabolic pathway that plays an important role in biosynthesis by providing one carbon unit. SHMT1 C1420T may lead to the abnormal biosynthesis involved in DNA synthesis and methylation, and it may eventually increase cancer susceptibility. Many epidemiologic studies have explored the association between C1420T polymorphism and...

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Source

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Identifiers

PMID: 26666829
DOI: 10.1186/s40880-015-0065-z
PMCID: PMC4699293

Genes

SHMT1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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