Article
Genetic profiling to determine risk of relapse-free survival in high-risk localized prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2014
Barnett Christine M, Heinrich Michael C, Lim Jeong, Nelson Dylan, Beadling Carol, Warrick Andrea, Neff Tanaya, Higano Celestia S, Garzotto Mark, Qian David, Corless Christopher L, Thomas George V, Beer Tomasz M
Abstract excerpt
PURPOSE: The characterization of actionable mutations in human tumors is a prerequisite for the development of individualized, targeted therapy. We examined the prevalence of potentially therapeutically actionable mutations in patients with high-risk clinically localized prostate cancer. EXPERIMENTAL DESIGN: Forty-eight samples of formalin-fixed paraffin-embedded prostatectomy tissue from a neoadjuvant...
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