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Article

Copy number alterations of <i>c‐MYC</i> and <i>PTEN</i> are prognostic factors for relapse after prostate cancer radiotherapy

26 Jan 2012

Abstract excerpt

Despite the use of PSA, Gleason score, and T-category as prognosticators in intermediate-risk prostate cancer, 20-40% of patients will fail local therapy. In order to optimize treatment approaches for intermediate-risk patients, additional genetic prognosticators are needed. Previous reports using array comparative genomic hybridization (aCGH) in radical prostatectomy cohorts suggested a combination of allelic...

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PMID: 22281794
DOI: 10.1002/cncr.26729

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