Article
ERG alterations and mTOR pathway activation in primary prostate carcinomas developing castration-resistance.
Pathology, research and practice - 1 Oct 2018
Vicentini Caterina, Cantù Cinzia, Antonello Davide, Simbolo Michele, Mafficini Andrea, Luchini Claudio, Rusev Borislav, Porcaro Antonio Benito, Iacovelli Roberto, Fassan Matteo, Corbo Vincenzo, Brunelli Matteo, Artibani Walter, Scarpa Aldo, Lawlor Rita T
Abstract excerpt
INTRODUCTION: One of the most common sites of distant metastasization of prostate cancer is bone, but to date reliable biomarkers able to predict the risk and timing of bone metastasization are still lacking. PATIENTS AND METHODS: Surgically resected paraffin embedded samples from 12 primary prostate cancers that developed metachronous bone metastasis at different time points were studied (six cases within 2...
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