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FISH analysis of 107 prostate cancers shows that PTEN genomic deletion is associated with poor clinical outcome

1 Aug 2007

Abstract excerpt

This study examines the clinical impact of PTEN genomic deletions using fluorescence in situ hybridisation (FISH) analysis of 107 prostate cancers, with follow-up information covering a period of up to 10 years. Tissue microarray analysis using interphase FISH indicated that hemizygous PTEN losses were present in 42/107 (39%) of prostatic adenocarcinomas, with a homozygous PTEN deletion observed in 5/107 (5%)...

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PMID: 17700571
DOI: 10.1038/sj.bjc.6603924

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FISH analysis of 107 prostate cancers shows that PTEN genomic deletion is associated with poor clinical outcomePMID 17700571Read ↗

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