Article
Tumour-based Mutational Profiles Predict Visceral Metastasis Outcome and Early Death in Prostate Cancer Patients.
European urology oncology - 1 Jun 2024
Cussenot Olivier, Timms Kirsten M, Perrot Emmanuel, Blanchet Pascal, Brureau Laurent, Solimeno Cara, Fromont Gaelle, Comperat Eva, Cancel-Tassin Geraldine
Abstract excerpt
BACKGROUND: Visceral metastases are known to occur in advanced prostate cancer, usually when the tumour is resistant to androgen deprivation and, have worse outcomes regardless of therapies. OBJECTIVE: To analyse genomic alterations in tumour samples according to their lymphatic, bone, and visceral metastatic stages and overall survival. DESIGN, SETTING, AND PARTICIPANTS: We selected 200 patients with metastatic...
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