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Article

Retrospective study testing next generation sequencing of selected cancer-associated genes in resected prostate cancer.

Oncotarget - 22 Mar 2016

Lo Iacono Marco, Buttigliero Consuelo, Monica Valentina, Bollito Enrico, Garrou Diletta, Cappia Susanna, Rapa Ida, Vignani Francesca, Bertaglia Valentina, Fiori Cristian, Papotti Mauro, Volante Marco, Scagliotti Giorgio V, Porpiglia Francesco, Tucci Marcello

Abstract excerpt

PURPOSE: Prostate cancer (PCa) has a highly heterogeneous outcome. Beyond Gleason Score, Prostate Serum Antigen and tumor stage, nowadays there are no biological prognostic factors to discriminate between indolent and aggressive tumors.The most common known genomic alterations are the TMPRSS-ETS translocation and mutations in the PI3K, MAPK pathways and in p53, RB and c-MYC genes.The aim of this retrospective...

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Source

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Identifiers

PMID: 26887047
DOI: 10.18632/oncotarget.7343
PMCID: PMC4924723

Genes

MET
FGFR3
KDR
KIT
MYC

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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