Article
Genetic markers associated with early cancer-specific mortality following prostatectomy.
Cancer - 1 Jul 2013
Liu Wennuan, Xie Chunmei C, Thomas Christopher Y, Kim Seong-Tae, Lindberg Johan, Egevad Lars, Wang Zhong, Zhang Zheng, Sun Jishan, Sun Jielin, Koty Patrick P, Kader A Karim, Cramer Scott D, Bova G Steven, Zheng S Lilly, Grönberg Henrik, Isaacs William B, Xu Jianfeng
Abstract excerpt
BACKGROUND: This study sought to identify novel effectors and markers of localized but potentially life-threatening prostate cancer (PCa), by evaluating chromosomal copy number alterations (CNAs) in tumors from patients who underwent prostatectomy and correlating these with clinicopathologic features and outcome. METHODS: CNAs in tumor DNA samples from 125 patients in the discovery cohort who underwent...
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