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Article

Role of the goat K222-PrP(C) polymorphic variant in prion infection resistance.

Journal of virology - 1 Mar 2014

Aguilar-Calvo Patricia, Espinosa Juan Carlos, Pintado Belén, Gutiérrez-Adán Alfonso, Alamillo Elia, Miranda Alberto, Prieto Irene, Bossers Alex, Andreoletti Olivier, Torres Juan María

Abstract excerpt

UNLABELLED: The prion protein-encoding gene (prnp) strongly influences the susceptibility of small ruminants to transmissible spongiform encephalopathies (TSEs). Hence, selective breeding programs have been implemented to increase sheep resistance to scrapie. For goats, epidemiological and experimental studies have provided some association between certain polymorphisms of the cellular prion protein (PrP(C)) and...

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Identifiers

PMID: 24352451
DOI: 10.1128/JVI.02074-13
PMCID: PMC3958052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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