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Article

Genetic and Pathological Follow-Up Study of Goats Experimentally and Naturally Exposed to a Sheep Scrapie Isolate.

Journal of virology - 1 Oct 2015

Maestrale Caterina, Cancedda Maria G, Pintus Davide, Masia Mariangela, Nonno Romolo, Ru Giuseppe, Carta Antonello, Demontis Francesca, Santucciu Cinzia, Ligios Ciriaco

Abstract excerpt

UNLABELLED: Thirty-seven goats carrying different prion protein genotypes (PRNP) were orally infected with a classical scrapie brain homogenate from wild-type (ARQ/ARQ) sheep and then mated to obtain 2 additional generations of offspring, which were kept in the same environment and allowed to be naturally exposed to scrapie. Occurrence of clinical or subclinical scrapie was observed in the experimentally infected...

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Source

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Identifiers

PMID: 26202249
DOI: 10.1128/JVI.01262-15
PMCID: PMC4577906

Genes

PRNP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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