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Incomplete protection of the K222 polymorphism of the prion protein gene after intracerebral exposure to caprine BSE in goats: preliminary follow-up in S127 carriers.

Veterinary research - 30 Apr 2026

Sola Diego, Pitarch José-Luis, Marín Belén, Raksa Helen-Caroline, Otero Alicia, Barillet Francis, Bouvier Frederic, Bolea Rosa, Bossers Alex, Andreoletti Olivier, Langeveld Jan, Badiola Juan-José, Acín Cristina

Abstract excerpt

Among small ruminants, natural bovine spongiform encephalopathy (BSE) has been confirmed only in goats, raising concern about the possible entry of caprine BSE into the food chain. Genetic selection for PRNP alleles associated with resistance to classical scrapie, particularly K222 and S127, has been proposed as a control strategy, but their effect on caprine BSE is unclear. Nine Alpine goats carrying different...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42063174
DOI: 10.1186/s13567-026-01760-8
PMCID: PMC13214245

Genes

PRNP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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Incomplete protection of the K222 polymorphism of the prion protein gene after intracerebral exposure to caprine BSE in goats: preliminary follow-up in S127 carriers.PMID 42063174Read ↗

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