Article
Variation in the prion protein sequence in Dutch goat breeds.
Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie - 1 Oct 2016
Windig J J, Hoving R A H, Priem J, Bossers A, van Keulen L J M, Langeveld J P M
Abstract excerpt
Scrapie is a neurodegenerative disease occurring in goats and sheep. Several haplotypes of the prion protein increase resistance to scrapie infection and may be used in selective breeding to help eradicate scrapie. In this study, frequencies of the allelic variants of the PrP gene are determined for six goat breeds in the Netherlands. Overall frequencies in Dutch goats were determined from 768 brain tissue...
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