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Article

Resistance to classical scrapie in experimentally challenged goats carrying mutation K222 of the prion protein gene.

Veterinary research - 1 Feb 2012

Acutis Pier Luigi, Martucci Francesca, D'Angelo Antonio, Peletto Simone, Colussi Silvia, Maurella Cristiana, Porcario Chiara, Iulini Barbara, Mazza Maria, Dell'atti Luana, Zuccon Fabio, Corona Cristiano, Martinelli Nicola, Casalone Cristina, Caramelli Maria, Lombardi Guerino

Abstract excerpt

Susceptibility of sheep to scrapie, a transmissible spongiform encephalopathy of small ruminants, is strongly influenced by polymorphisms of the prion protein gene (PRNP). Breeding programs have been implemented to increase scrapie resistance in sheep populations; though desirable, a similar approach has not yet been applied in goats. European studies have now suggested that several polymorphisms can modulate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22296670
DOI: 10.1186/1297-9716-43-8
PMCID: PMC3296670

Genes

PRNP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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