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Article

TCTP directly regulates ATM activity to control genome stability and organ development in Drosophila melanogaster.

Nature communications - 1 Jan 2013

Hong Sung-Tae, Choi Kwang-Wook

Abstract excerpt

Translationally controlled tumour protein (TCTP) is implicated in growth regulation and cancer. Recently, human TCTP has been suggested to play a role in the DNA damage response by forming a complex with ataxia telangiectasia-mutated (ATM) kinase . However, the exact nature of this interaction and its roles in vivo remained unclear. Here, we utilize Drosophila as an animal model to study the nuclear function of...

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Source

Identifiers

PMID: 24352200
DOI: 10.1038/ncomms3986

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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