Article
Molecular genetic characterization of Drosophila ATM conserved functional domains.
Genome - 1 Oct 2010
Pedersen M, Tiong S, Campbell S D
Abstract excerpt
ATM-related kinases promote repair of DNA double-strand breaks and maintenance of chromosome telomeres, functions that are essential for chromosome structural integrity in all eukaryotic organisms. In humans, loss of ATM function is associated with ataxia telangiectasia, a neurodegenerative disease characterized by extreme sensitivity to DNA damage. Drosophila melanogaster has recently emerged as a useful animal...
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