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Nuclear Argonaute protein NRDE-3 switches small RNA partners during embryogenesis to mediate temporal-specific gene regulatory activity

2024-07-30

Abstract excerpt

RNA interference (RNAi) is a conserved gene regulation mechanism that utilizes the Argonaute protein and their associated small RNAs to exert regulatory function on complementary transcripts. While the majority of germline-expressed RNAi pathway components reside in perinuclear germ granules, it is unknown whether and how RNAi pathways are spatially organized in other cell types. Here we find that the small RNA bi...

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Literature Corpus work
b9a4604c-df2b-53db-879c-4cb95f682bbc
DOI
10.1101/2024.07.29.605686
Open publication

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Nuclear Argonaute protein NRDE-3 switches small RNA partners during embryogenesis to mediate temporal-specific gene regulatory activityDOI 10.1101/2024.07.29.605686
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