Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The viral F-box protein P0 induces an ER-derived autophagy degradation pathway for the clearance of membrane-bound AGO1

18 Oct 2019

Abstract excerpt

Significance The viral suppressor of RNA silencing P0 is known to target plant antiviral ARGONAUTE (AGO) proteins for degradation via an autophagy-related process. Here we utilized P0 to gain insight into the cellular degradation dynamics of AGO1, the major plant effector of RNA silencing. We revealed that P0 targets endoplasmic reticulum (ER)-associated AGO1 by inducing the formation of ER-related bodies that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Mosquito-borne diseases and control
Share to Plant Virus Research Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31628252
DOI: 10.1073/pnas.1912222116

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The viral F-box protein P0 induces an ER-derived autophagy degradation pathway for the clearance of membrane-bound AGO1PMID 31628252Read ↗

Degradation of the antiviral component ARGONAUTE1 by the autophagy pathwaySemantic proximity Read ↗

The miRNA pathway limits AGO1 availability during siRNA-mediated PTGS defense against exogenous RNA.Semantic proximity Read ↗

A small peptide inhibits siRNA amplification in plants by mediating autophagic degradation of SGS3/RDR6 bodies.Semantic proximity Read ↗

The Great Game between Plants and Viruses: A Focus on Protein HomeostasisSemantic proximity Read ↗

Plant ARGONAUTES.Semantic proximity Read ↗

VCP Machinery Mediates Autophagic Degradation of Empty ArgonauteSemantic proximity Read ↗

A specialized ARGONAUTE enables trans-species RNA interference in plant immunitySemantic proximity Read ↗

The N-coil and the globular N-terminal domain of plant ARGONAUTE1 are interaction hubs for regulatory factors.Semantic proximity Read ↗

The developmental outcomes of P0-mediated ARGONAUTE destabilization in tomato.Semantic proximity Read ↗

Viral Protein Inhibits RISC Activity by Argonaute Binding through Conserved WG/GW MotifsSemantic proximity Read ↗

Functional Characterization of RNA Silencing Suppressor P0 from Pea Mild Chlorosis Virus.Semantic proximity Read ↗

Cutting through the stress: RNA decay pathways at the endoplasmic reticulumSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.