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<i>Wolbachia</i> uses a host microRNA to regulate transcripts of a methyltransferase, contributing to dengue virus inhibition in <i>Aedes aegypti</i>

3 Jun 2013

Abstract excerpt

The endosymbiont Wolbachia is common among insects and known for the reproductive manipulations it exerts on hosts as well as inhibition of virus replication in their hosts. Recently, we showed that Wolbachia uses host microRNAs to manipulate host gene expression for its efficient maintenance in the dengue mosquito vector, Aedes aegypti. Cytosine methylation is mediated by a group of proteins called DNA...

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PMID: 23733960
DOI: 10.1073/pnas.1303603110

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