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Article

CXCL10 gene promoter polymorphism -1447A>G correlates with plasma CXCL10 levels and is associated with male susceptibility to cerebral malaria.

PloS one - 1 Jan 2013

Wilson Nana, Driss Adel, Solomon Wesley, Dickinson-Copeland Carmen, Salifu Hassana, Jain Vidhan, Singh Neeru, Stiles Jonathan

Abstract excerpt

The risk factors for cerebral malaria (CM) and the wide variation in clinical manifestations of malaria are poorly understood. Recent studies indicate that interferon gamma inducible chemokine, CXCL10, is a strong predictor of both human and experimental cerebral malaria. Increased plasma and cerebrospinal fluid levels of CXCL10 were tightly associated with fatal CM in Indian and Ghanaian patients. In the present...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

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Share to Promoter Regions, Genetic

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Source

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Identifiers

PMID: 24349056
DOI: 10.1371/journal.pone.0081329
PMCID: PMC3857834

Genes

CXCL10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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