Article
PRELIMINARY REPORT ON THE PUTATIVE ASSOCIATION OF IL10 -3575 T/A GENETIC POLYMORPHISM WITH MALARIA SYMPTOMS.
Revista do Instituto de Medicina Tropical de Sao Paulo - 1 Jan 2016
Domingues Wilson, Kanunfre Kelly Aparecida, Rodrigues Jonatas Cristian, Teixeira Leandro Emidio, Yamamoto Lidia, Okay Thelma Suely
Abstract excerpt
Only a small percentage of individuals living in endemic areas develop severe malaria suggesting that host genetic factors may play a key role. This study has determined the frequency of single nucleotide polymorphisms (SNPs) in some pro and anti-inflammatory cytokine gene sequences: IL6 (-174; rs1800795), IL12p40 (+1188; rs3212227), IL4 (+33; rs2070874), IL10 (-3575; rs1800890) and TGFb1 (+869; rs1800470), by...
