Article
EndoU is a novel regulator of AICD during peripheral B cell selection.
The Journal of experimental medicine - 13 Jan 2014
Poe Jonathan C, Kountikov Evgueni I, Lykken Jacquelyn M, Natarajan Abirami, Marchuk Douglas A, Tedder Thomas F
Abstract excerpt
Balanced transmembrane signals maintain a competent peripheral B cell pool limited in self-reactive B cells that may produce pathogenic autoantibodies. To identify molecules regulating peripheral B cell survival and tolerance to self-antigens (Ags), a gene modifier screen was performed with B cel...
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