Article
The human CFTR protein expressed in CHO cells activates aquaporin-3 in a cAMP-dependent pathway: study by digital holographic microscopy.
Journal of cell science - 1 Feb 2014
Jourdain Pascal, Becq Frédéric, Lengacher Sylvain, Boinot Clément, Magistretti Pierre J, Marquet Pierre
Abstract excerpt
The transmembrane water movements during cellular processes and their relationship to ionic channel activity remain largely unknown. As an example, in epithelial cells it was proposed that the movement of water could be directly linked to cystic fibrosis transmembrane conductance regulator (CFTR) protein activity through a cAMP-stimulated aqueous pore, or be dependent on aquaporin. Here, we used digital...
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