Article
Cystic fibrosis transmembrane conductance regulator activates water conductance in Xenopus oocytes.
Pflugers Archiv : European journal of physiology - 1 Nov 1997
Schreiber R, Greger R, Nitschke R, Kunzelmann K
Abstract excerpt
Multiple properties have been attributed to the cystic fibrosis transmembrane conductance regulator (CFTR), the gene product which is mutated in cystic fibrosis (CF). In this context it has been reported that CFTR transports water. In the present study we demonstrate that expression of wild-type...
Topics
- 1-Methyl-3-isobutylxanthine
- Animals
- Cystic Fibrosis Transmembrane Conductance Regulator
- Electric Conductivity
- Female
- Mutation
- Oocytes
- Patch-Clamp Techniques
- Permeability
- Phosphodiesterase Inhibitors
- Water
- Xenopus laevis