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Article

Control of excitatory and inhibitory synapse formation by neuroligins.

Science (New York, N.Y.) - 25 Feb 2005

Chih Ben, Engelman Holly, Scheiffele Peter

Abstract excerpt

The normal function of neural networks depends on a delicate balance between excitatory and inhibitory synaptic inputs. Synapse formation is thought to be regulated by bidirectional signaling between pre- and postsynaptic cells. We demonstrate that members of the Neuroligin family promote postsynaptic differentiation in cultured rat hippocampal neurons. Down-regulation of neuroligin isoform expression by RNA...

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Identifiers

PMID: 15681343
DOI: 10.1126/science.1107470

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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