Article
A novel PITX2c loss-of-function mutation associated with familial atrial fibrillation.
European journal of medical genetics - 1 Jan 2014
Wang Jun, Zhang Dai-Fu, Sun Yu-Min, Yang Yi-Qing
Abstract excerpt
Atrial fibrillation (AF) represents the most prevalent form of sustained cardiac arrhythmia and contributes substantially to cardiovascular morbidity and mortality. Aggregating evidence demonstrates that genetic risk factors play an important role in the pathogenesis of AF. However, AF is a genetically heterogeneous disease and the genetic defects responsible for AF in an overwhelming majority of patients remain...
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