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Article

PITX2C loss-of-function mutations responsible for idiopathic atrial fibrillation.

Clinics (Sao Paulo, Brazil) - 1 Jan 2014

Qiu Xing-Biao, Xu Ying-Jia, Li Ruo-Gu, Xu Lei, Liu Xu, Fang Wei-Yi, Yang Yi-Qing, Qu Xin-Kai

Abstract excerpt

OBJECTIVE: This study aimed to identify novel PITX2c mutations responsible for idiopathic atrial fibrillation. METHODS: A cohort of 210 unrelated patients with idiopathic atrial fibrillation and 200 unrelated, ethnically matched healthy individuals used as controls were recruited. The whole coding exons and splice junctions of the PITX2c gene, which encodes a paired-like homeobox transcription factor required for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24473555
DOI: 10.6061/clinics/2014(01)03
PMCID: PMC3870307

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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