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Article

Novel PITX2c loss-of-function mutations associated with complex congenital heart disease.

International journal of molecular medicine - 1 May 2014

Wei Dong, Gong Xiao-Hui, Qiu Gang, Wang Juan, Yang Yi-Qing

Abstract excerpt

Congenital heart disease (CHD) is the most common form of birth defect in humans and is the leading non-infectious cause of infant mortality. Emerging evidence strongly suggests that genetic risk factors play an important role in the pathogenesis of CHD. However, CHD is of pronounced genetic heterogeneity, and the genetic defects responsible for CHD in an overwhelming majority of patients remain unclear. In this...

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Share to Genetic Predisposition to Disease
Share to Heart Defects, Congenital

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homeobox Protein PITX2

Share to Homeodomain Proteins

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Source

Identifiers

PMID: 24604414
DOI: 10.3892/ijmm.2014.1689

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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