Article
A novel GATA5 loss-of-function mutation underlies lone atrial fibrillation.
International journal of molecular medicine - 1 Jan 2013
Wang Xin-Hua, Huang Cong-Xin, Wang Qian, Li Ruo-Gu, Xu Ying-Jia, Liu Xu, Fang Wei-Yi, Yang Yi-Qing
Abstract excerpt
Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, is associated with significantly increased morbidity and mortality. Cumulative evidence highlights the importance of genetic defects in the pathogenesis of AF. However, AF is of remarkable heterogeneity and the genetic determinants of AF in a vast majority of patients remain illusive. In this...
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